Self-publishing is a great chance for many authors but I imagine that it's not for everyone. Even with physical distribution out of the picture: having a publisher means having an experienced and professional editor, book cover designer and marketing department. So I don't think that established publishing houses will disappear, but they of course have to adjust to a changing market, too. As a consumer, I'm still not completely satisfied with the current available eBook readers. I tried an older Sony PRS-505, which only becomes usable with an alternative firmware. Then I recently got myself a new iPad (mostly for software development) but the active display is not for everyone, especially when reading in bed before going to sleep.
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